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Improvement of cytomegalovirus pp65 DNA vaccine efficacy by co-administration of siRNAs targeting BAK and BAX

The efficacy of DNA vaccines may be improved by small interfering (si)RNA adjuvants targeting pro-apoptotic genes. The aim of the present study was to investigate the capacity of siRNAs targeting B-cell lymphoma 2 homologous antagonist killer (BAK) and B-cell lymphoma 2-associated X protein (BAX) to...

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Detalles Bibliográficos
Autores principales: Liu, Jixiao, Feng, Keke, Zhao, Lu, Luo, Haining, Zhu, Yingjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450512/
https://www.ncbi.nlm.nih.gov/pubmed/28587400
http://dx.doi.org/10.3892/etm.2017.4385