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Discs-large (DLG) is clustered by presynaptic innervation and regulates postsynaptic glutamate receptor subunit composition in Drosophila

BACKGROUND: Drosophila discs-large (DLG) is the sole representative of a large class of mammalian MAGUKs, including human DLG, SAP 97, SAP102, and PSD-95. MAGUKs are thought to be critical for postsynaptic assembly at glutamatergic synapses. However, glutamate receptor cluster formation has never be...

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Detalles Bibliográficos
Autores principales: Chen, Kaiyun, Featherstone, David E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC545058/
https://www.ncbi.nlm.nih.gov/pubmed/15638945
http://dx.doi.org/10.1186/1741-7007-3-1