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Mediation of insulin growth factor-1 in Alzheimer's disease and the mechanism of PRNP genetic expression and the PI3K/Akt signaling pathway

The aim of the study was to examine the mediation of insulin growth factor-1 (IGF-1) in Alzheimer's disease (AD), as well as the underlying mechanism of the PRNP genetic expression and PI3K/Akt signaling pathway. The Aβ(25–35)-incubated rat adrenal pheochromocytoma cell (PC12) in vitro was esta...

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Detalles Bibliográficos
Autores principales: Jiang, Guohong, Wang, Changming, Zhang, Jun, Liu, Haijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450607/
https://www.ncbi.nlm.nih.gov/pubmed/28587338
http://dx.doi.org/10.3892/etm.2017.4320