HDAC8 Prevents Anthrax Lethal Toxin-induced Cell Cycle Arrest through Silencing PTEN in Human Monocytic THP-1 Cells

Anthrax lethal toxin (LeTx) is a cytotoxic virulence factor that causes cell cycle arrest and cell death in various cell types. However, susceptibility to the cytotoxic effects varies depending on cell types. In proliferating monocytes, LeTx has only transient cytotoxic effects due to activation of...

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Detalles Bibliográficos
Autores principales: Ha, Soon-Duck, Cho, Woohyun, Kim, Sung Ouk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450710/
https://www.ncbi.nlm.nih.gov/pubmed/28509866
http://dx.doi.org/10.3390/toxins9050162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450710/
https://www.ncbi.nlm.nih.gov/pubmed/28509866
http://dx.doi.org/10.3390/toxins9050162

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