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RBC Adherence of Immune Complexes Containing Botulinum Toxin Improves Neutralization and Macrophage Uptake

In the paralytic disease botulism, the botulinum neurotoxin (BoNT) passes through the bloodstream to reach and inactivate neuromuscular junctions. Monoclonal antibodies (mAbs) may be useful BoNT countermeasures, as mAb combinations can rapidly clear BoNT from the blood circulation. We have previousl...

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Detalles Bibliográficos
Autores principales: Al-Saleem, Fetweh H., Sharma, Rashmi, Puligedda, Rama Devudu, Elias, Md., Kattala, Chandana Devi, Simon, Paul M., Simpson, Lance L., Dessain, Scott K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450721/
https://www.ncbi.nlm.nih.gov/pubmed/28534855
http://dx.doi.org/10.3390/toxins9050173