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Immunological Predictors of Nonresponse to Directly Acting Antiviral Therapy in Patients With Chronic Hepatitis C and Decompensated Cirrhosis

BACKGROUND: Sustained virological response rates (SVRs) to directly acting antiviral (DAA) therapy for hepatitis C virus (HCV) are lower in decompensated cirrhosis. Markers of innate immunity predict nonresponse to interferon-based HCV treatment; however, whether they are associated with the respons...

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Detalles Bibliográficos
Autores principales: Childs, Kate, Merritt, Elliot, Considine, Aisling, Sanchez-Fueyo, Alberto, Agarwal, Kosh, Martinez-Llordella, Marc, Carey, Ivana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450903/
https://www.ncbi.nlm.nih.gov/pubmed/28584852
http://dx.doi.org/10.1093/ofid/ofx067