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CRISPR-Cas Genome Surgery in Ophthalmology

Genetic disease affecting vision can significantly impact patient quality of life. Gene therapy seeks to slow the progression of these diseases by treating the underlying etiology at the level of the genome. Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated sys...

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Detalles Bibliográficos
Autores principales: DiCarlo, James E., Sengillo, Jesse D., Justus, Sally, Cabral, Thiago, Tsang, Stephen H., Mahajan, Vinit B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450921/
https://www.ncbi.nlm.nih.gov/pubmed/28573077
http://dx.doi.org/10.1167/tvst.6.3.13