Comparison of single-marker and multi-marker tests in rare variant association studies of quantitative traits

In genetic association studies of rare variants, low statistical power and potential violations of established estimator properties are among the main challenges of association tests. Multi-marker tests (MMTs) have been proposed to target these challenges, but any comparison with single-marker tests...

Descripción completa

Detalles Bibliográficos
Autores principales: Konigorski, Stefan, Yilmaz, Yildiz E., Pischon, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451057/
https://www.ncbi.nlm.nih.gov/pubmed/28562689
http://dx.doi.org/10.1371/journal.pone.0178504

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451057/
https://www.ncbi.nlm.nih.gov/pubmed/28562689
http://dx.doi.org/10.1371/journal.pone.0178504

Ejemplares similares