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Comparison of single-marker and multi-marker tests in rare variant association studies of quantitative traits
In genetic association studies of rare variants, low statistical power and potential violations of established estimator properties are among the main challenges of association tests. Multi-marker tests (MMTs) have been proposed to target these challenges, but any comparison with single-marker tests...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451057/ https://www.ncbi.nlm.nih.gov/pubmed/28562689 http://dx.doi.org/10.1371/journal.pone.0178504 |