Cargando…

Synthetic, Functional Thymidine-Derived Polydeoxyribonucleotide Analogues from a Six-Membered Cyclic Phosphoester

[Image: see text] A grand challenge that crosses synthetic chemistry and biology is the scalable production of functional analogues of biomacromolecules. We have focused our attention on the use of deoxynucleoside building blocks bearing non-natural bases to develop a synthetic methodology that allo...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsao, Yi-Yun Timothy, Wooley, Karen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451148/
https://www.ncbi.nlm.nih.gov/pubmed/28394136
http://dx.doi.org/10.1021/jacs.7b01116