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Antibody Reactivity of B Cells in Lupus Patients with Increased Disease Activity and ARID3a Expression
Earlier studies showed that the DNA-binding protein, Bright/ARID3a bound to a subset of human and mouse immunoglobulin heavy chain promoters where it enhanced expression. Indeed, mice with transgenic expression of ARID3a in all B lymphocytes have expanded MZ B cells and produce anti-nuclear antibodi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451160/ https://www.ncbi.nlm.nih.gov/pubmed/28580178 http://dx.doi.org/10.3390/antib4040354 |