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Cellular levels of Grb2 and cytoskeleton stability are correlated in a neurodegenerative scenario

Alzheimer's disease (AD) manifests as neuronal loss. On the premise of Grb2 overexpression in AD mouse brain and brain tissues of AD patients, our study primarily focuses on the stability of cytoskeletal proteins in the context of degenerative AD-like conditions. Two predominant molecular featu...

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Detalles Bibliográficos
Autores principales: Majumder, Piyali, Roy, Kasturi, Singh, Brijesh Kumar, Jana, Nihar Ranjan, Mukhopadhyay, Debashis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451165/
https://www.ncbi.nlm.nih.gov/pubmed/28360125
http://dx.doi.org/10.1242/dmm.027748