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A differential autophagy-dependent response to DNA double-strand breaks in bone marrow mesenchymal stem cells from sporadic ALS patients

Amyotrophic lateral sclerosis (ALS) is an incurable motor neurodegenerative disease caused by a diversity of genetic and environmental factors that leads to neuromuscular degeneration and has pathophysiological implications in non-neural systems. Our previous work showed abnormal levels of mRNA expr...

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Detalles Bibliográficos
Autores principales: Wald-Altman, Shane, Pichinuk, Edward, Kakhlon, Or, Weil, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451167/
https://www.ncbi.nlm.nih.gov/pubmed/28213588
http://dx.doi.org/10.1242/dmm.027938