Cargando…
A differential autophagy-dependent response to DNA double-strand breaks in bone marrow mesenchymal stem cells from sporadic ALS patients
Amyotrophic lateral sclerosis (ALS) is an incurable motor neurodegenerative disease caused by a diversity of genetic and environmental factors that leads to neuromuscular degeneration and has pathophysiological implications in non-neural systems. Our previous work showed abnormal levels of mRNA expr...
Autores principales: | Wald-Altman, Shane, Pichinuk, Edward, Kakhlon, Or, Weil, Miguel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451167/ https://www.ncbi.nlm.nih.gov/pubmed/28213588 http://dx.doi.org/10.1242/dmm.027938 |
Ejemplares similares
-
Two Potential Biomarkers Identified in Mesenchymal Stem Cells and Leukocytes of Patients with Sporadic Amyotrophic lateral Sclerosis
por: Nachmany, Henny, et al.
Publicado: (2012) -
Minerval (2-hydroxyoleic acid) causes cancer cell selective toxicity by uncoupling oxidative phosphorylation and compromising bioenergetic compensation capacity
por: Massalha, Wessal, et al.
Publicado: (2019) -
In Vitro Expansion of Bone Marrow Derived Mesenchymal Stem Cells Alters DNA Double Strand Break Repair of Etoposide Induced DNA Damage
por: Hare, Ian, et al.
Publicado: (2016) -
Proteins pinpoint double strand breaks
por: Cox, Michael M
Publicado: (2013) -
Choreographing the Double Strand Break Response: Ubiquitin and SUMO Control of Nuclear Architecture
por: Harding, Shane M., et al.
Publicado: (2016)