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Vulnerability of primary neurons derived from Tg2576 Alzheimer mice to oxygen and glucose deprivation: role of intraneuronal amyloid-β accumulation and astrocytes

Microvascular dysfunction is considered an integral part of Alzheimer disease (AD) pathogenesis, but the possible relationship between amyloid pathology, microvascular dysfunction and cell death is still unclear. In order to investigate the influence of intraneuronal amyloid-β (Aβ) accumulation on v...

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Detalles Bibliográficos
Autores principales: Baldassarro, Vito Antonio, Marchesini, Alessandra, Giardino, Luciana, Calzà, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451168/
https://www.ncbi.nlm.nih.gov/pubmed/28237964
http://dx.doi.org/10.1242/dmm.028001