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Upregulation of CB(2) receptors in reactive astrocytes in canine degenerative myelopathy, a disease model of amyotrophic lateral sclerosis

Targeting of the CB(2) receptor results in neuroprotection in the SOD1(G93A) mutant mouse model of amyotrophic lateral sclerosis (ALS). The neuroprotective effects of CB(2) receptors are facilitated by their upregulation in the spinal cord of the mutant mice. Here, we investigated whether similar CB...

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Detalles Bibliográficos
Autores principales: Fernández-Trapero, María, Espejo-Porras, Francisco, Rodríguez-Cueto, Carmen, Coates, Joan R., Pérez-Díaz, Carmen, de Lago, Eva, Fernández-Ruiz, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451172/
https://www.ncbi.nlm.nih.gov/pubmed/28069688
http://dx.doi.org/10.1242/dmm.028373