Does hypoxia play a role in the development of sarcopenia in humans? Mechanistic insights from the Caudwell Xtreme Everest Expedition

OBJECTIVES: Sarcopenia refers to the involuntary loss of skeletal muscle and is a predictor of physical disability/mortality. Its pathogenesis is poorly understood, although roles for altered hypoxic signaling, oxidative stress, adipokines and inflammatory mediators have been suggested. Sarcopenia a...

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Detalles Bibliográficos
Autores principales: Wandrag, Liesl, Siervo, Mario, Riley, Heather L., Khosravi, Maryam, Fernandez, Bernadette O., Leckstrom, Carl A., Martin, Daniel S., Mitchell, Kay, Levett, Denny Z.H., Montgomery, Hugh E., Mythen, Monty G., Stroud, Michael A., Grocott, Michael P.W., Feelisch, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451185/
https://www.ncbi.nlm.nih.gov/pubmed/28570949
http://dx.doi.org/10.1016/j.redox.2017.05.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451185/
https://www.ncbi.nlm.nih.gov/pubmed/28570949
http://dx.doi.org/10.1016/j.redox.2017.05.004

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