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HSP105 prevents depression-like behavior by increasing hippocampal brain-derived neurotrophic factor levels in mice

Heat shock proteins (HSPs) are stress-induced chaperones that are involved in neurological disease. Although increasingly implicated in behavioral disorders, the mechanisms of HSP action, and the relevant functional pathways, are still unclear. We examined whether oral administration of geranylgeran...

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Detalles Bibliográficos
Autores principales: Hashikawa, Naoya, Utaka, Yuta, Ogawa, Takumi, Tanoue, Ryo, Morita, Yuna, Yamamoto, Sayumi, Yamaguchi, Satoru, Kayano, Masafumi, Zamami, Yoshito, Hashikawa-Hobara, Narumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451194/
https://www.ncbi.nlm.nih.gov/pubmed/28580422
http://dx.doi.org/10.1126/sciadv.1603014