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Competition between histone and transcription factor binding regulates the onset of transcription in zebrafish embryos

Upon fertilization, the genome of animal embryos remains transcriptionally inactive until the maternal-to-zygotic transition. At this time, the embryo takes control of its development and transcription begins. How the onset of zygotic transcription is regulated remains unclear. Here, we show that a...

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Detalles Bibliográficos
Autores principales: Joseph, Shai R, Pálfy, Máté, Hilbert, Lennart, Kumar, Mukesh, Karschau, Jens, Zaburdaev, Vasily, Shevchenko, Andrej, Vastenhouw, Nadine L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451213/
https://www.ncbi.nlm.nih.gov/pubmed/28425915
http://dx.doi.org/10.7554/eLife.23326