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Cdk6 contributes to cytoskeletal stability in erythroid cells

Mice lacking Cdk6 kinase activity suffer from mild anemia accompanied by elevated numbers of Ter119(+) cells in the bone marrow. The animals show hardly any alterations in erythroid development, indicating that Cdk6 is not required for proliferation and maturation of erythroid cells. There is also n...

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Detalles Bibliográficos
Autores principales: Uras, Iris Z., Scheicher, Ruth M., Kollmann, Karoline, Glösmann, Martin, Prchal-Murphy, Michaela, Tigan, Anca S., Fux, Daniela A., Altamura, Sandro, Neves, Joana, Muckenthaler, Martina U., Bennett, Keiryn L., Kubicek, Stefan, Hinds, Philip W., von Lindern, Marieke, Sexl, Veronika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451331/
https://www.ncbi.nlm.nih.gov/pubmed/28255017
http://dx.doi.org/10.3324/haematol.2016.159947