Targeting the 5T4 oncofetal glycoprotein with an antibody drug conjugate (A1mcMMAF) improves survival in patient-derived xenograft models of acute lymphoblastic leukemia

Outcome in childhood acute lymphoblastic leukemia is prognosticated from levels of minimal residual disease after remission induction therapy. Higher levels of minimal residual disease are associated with inferior results even with intensification of therapy, thus suggesting that identification and...

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Detalles Bibliográficos
Autores principales: McGinn, Owen J., Krishnan, Shekhar, Bourquin, Jean-Pierre, Sapra, Puja, Dempsey, Clare, Saha, Vaskar, Stern, Peter L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451339/
https://www.ncbi.nlm.nih.gov/pubmed/28341731
http://dx.doi.org/10.3324/haematol.2016.158485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451339/
https://www.ncbi.nlm.nih.gov/pubmed/28341731
http://dx.doi.org/10.3324/haematol.2016.158485

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