Combinatorial Delivery of Dual and Triple TLR Agonists via Polymeric Pathogen-like Particles Synergistically Enhances Innate and Adaptive Immune Responses

Despite decades of research very few vaccine-adjuvants have received FDA approval. Two fundamental challenges plague clinical translation of vaccine-adjuvants: reducing acute toxicities that result from systemic diffusion of many soluble adjuvants, and delivering multiple adjuvants at the same time...

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Detalles Bibliográficos
Autores principales: Madan-Lala, Ranjna, Pradhan, Pallab, Roy, Krishnendu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451393/
https://www.ncbi.nlm.nih.gov/pubmed/28566683
http://dx.doi.org/10.1038/s41598-017-02804-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451393/
https://www.ncbi.nlm.nih.gov/pubmed/28566683
http://dx.doi.org/10.1038/s41598-017-02804-y

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