A PPARγ-dependent miR-424/503-CD40 axis regulates inflammation mediated angiogenesis

Activation of the endothelium by pro-inflammatory stimuli plays a key role in the pathogenesis of a multitude of vascular diseases. Angiogenesis is a crucial component of the vascular response associated with inflammatory signaling. The CD40/CD40 ligand dyad in endothelial cells (EC) has a central r...

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Detalles Bibliográficos
Autores principales: Lee, Aram, Papangeli, Irinna, Park, Youngsook, Jeong, Ha-neul, Choi, Jihea, Kang, Hyesoo, Jo, Ha-neul, Kim, Jongmin, Chun, Hyung J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451412/
https://www.ncbi.nlm.nih.gov/pubmed/28566713
http://dx.doi.org/10.1038/s41598-017-02852-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451412/
https://www.ncbi.nlm.nih.gov/pubmed/28566713
http://dx.doi.org/10.1038/s41598-017-02852-4

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