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A PPARγ-dependent miR-424/503-CD40 axis regulates inflammation mediated angiogenesis
Activation of the endothelium by pro-inflammatory stimuli plays a key role in the pathogenesis of a multitude of vascular diseases. Angiogenesis is a crucial component of the vascular response associated with inflammatory signaling. The CD40/CD40 ligand dyad in endothelial cells (EC) has a central r...
Autores principales: | Lee, Aram, Papangeli, Irinna, Park, Youngsook, Jeong, Ha-neul, Choi, Jihea, Kang, Hyesoo, Jo, Ha-neul, Kim, Jongmin, Chun, Hyung J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451412/ https://www.ncbi.nlm.nih.gov/pubmed/28566713 http://dx.doi.org/10.1038/s41598-017-02852-4 |
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