Targeted radionuclide therapy with astatine-211: Oxidative dehalogenation of astatobenzoate conjugates

(211)At is a most promising radionuclide for targeted alpha therapy. However, its limited availability and poorly known basic chemistry hamper its use. Based on the analogy with iodine, labelling is performed via astatobenzoate conjugates, but in vivo deastatination occurs, particularly when the con...

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Detalles Bibliográficos
Autores principales: Teze, David, Sergentu, Dumitru-Claudiu, Kalichuk, Valentina, Barbet, Jacques, Deniaud, David, Galland, Nicolas, Maurice, Rémi, Montavon, Gilles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451414/
https://www.ncbi.nlm.nih.gov/pubmed/28566709
http://dx.doi.org/10.1038/s41598-017-02614-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451414/
https://www.ncbi.nlm.nih.gov/pubmed/28566709
http://dx.doi.org/10.1038/s41598-017-02614-2

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