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Targeted radionuclide therapy with astatine-211: Oxidative dehalogenation of astatobenzoate conjugates
(211)At is a most promising radionuclide for targeted alpha therapy. However, its limited availability and poorly known basic chemistry hamper its use. Based on the analogy with iodine, labelling is performed via astatobenzoate conjugates, but in vivo deastatination occurs, particularly when the con...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451414/ https://www.ncbi.nlm.nih.gov/pubmed/28566709 http://dx.doi.org/10.1038/s41598-017-02614-2 |