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Dibutyl phthalate induced testicular dysgenesis originates after seminiferous cord formation in rats

Administration of dibutyl phthalate (DBP) to pregnant rats causes reproductive disorders in male offspring, resulting from suppression of intratesticular testosterone, and is used as a model for human testicular dysgenesis syndrome (TDS). DBP exposure in pregnancy induces focal dysgenetic areas in f...

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Detalles Bibliográficos
Autores principales: Lara, Nathália L. M., van den Driesche, Sander, Macpherson, Sheila, França, Luiz R., Sharpe, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451485/
https://www.ncbi.nlm.nih.gov/pubmed/28566680
http://dx.doi.org/10.1038/s41598-017-02684-2