Structural basis for ligand capture and release by the endocytic receptor ApoER2

Apolipoprotein E receptor 2 (ApoER2) is a close homologue of low‐density lipoprotein receptor (LDLR) that mediates the endocytosis of ligands, including LDL particles. LDLR family members have been presumed to explore a large conformational space to capture ligands in the extended conformation at th...

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Detalles Bibliográficos
Autores principales: Hirai, Hidenori, Yasui, Norihisa, Yamashita, Keitaro, Tabata, Sanae, Yamamoto, Masaki, Takagi, Junichi, Nogi, Terukazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452030/
https://www.ncbi.nlm.nih.gov/pubmed/28446613
http://dx.doi.org/10.15252/embr.201643521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452030/
https://www.ncbi.nlm.nih.gov/pubmed/28446613
http://dx.doi.org/10.15252/embr.201643521

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