Cargando…

Molecular basis for Cdk1‐regulated timing of Mis18 complex assembly and CENP‐A deposition

The centromere, a chromosomal locus that acts as a microtubule attachment site, is epigenetically specified by the enrichment of CENP‐A nucleosomes. Centromere maintenance during the cell cycle requires HJURP‐mediated CENP‐A deposition, a process regulated by the Mis18 complex (Mis18α/Mis18β/Mis18BP...

Descripción completa

Detalles Bibliográficos
Autores principales: Spiller, Frances, Medina‐Pritchard, Bethan, Abad, Maria Alba, Wear, Martin A, Molina, Oscar, Earnshaw, William C, Jeyaprakash, A Arockia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452045/
https://www.ncbi.nlm.nih.gov/pubmed/28377371
http://dx.doi.org/10.15252/embr.201643564