Transient transcription factor (OSKM) expression is key towards clinical translation of in vivo cell reprogramming

Reprogramming adult, fully differentiated cells to pluripotency in vivo via Oct3/4, Sox2, Klf4 and c‐Myc (OSKM) overexpression has proved feasible in various independent studies and could be used to induce tissue regeneration owing to the proliferative capacity and differentiation potential of the r...

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Detalles Bibliográficos
Autores principales: de Lázaro, Irene, Cossu, Giulio, Kostarelos, Kostas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452046/
https://www.ncbi.nlm.nih.gov/pubmed/28455313
http://dx.doi.org/10.15252/emmm.201707650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452046/
https://www.ncbi.nlm.nih.gov/pubmed/28455313
http://dx.doi.org/10.15252/emmm.201707650

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