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Palmitoleic Acid Inhibits RANKL-Induced Osteoclastogenesis and Bone Resorption by Suppressing NF-κB and MAPK Signalling Pathways

Osteoclasts are large, multinucleated cells that are responsible for the breakdown or resorption of bone during bone remodelling. Studies have shown that certain fatty acids (FAs) can increase bone formation, reduce bone loss, and influence total bone mass. Palmitoleic acid (PLA) is a 16-carbon, mon...

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Detalles Bibliográficos
Autores principales: van Heerden, Bernadette, Kasonga, Abe, Kruger, Marlena C., Coetzee, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452171/
https://www.ncbi.nlm.nih.gov/pubmed/28452958
http://dx.doi.org/10.3390/nu9050441