Cargando…
Allosteric DNA nanoswitches for controlled release of a molecular cargo triggered by biological inputs
Here we demonstrate the rational design of a new class of DNA-based nanoswitches which are allosterically regulated by specific biological targets, antibodies and transcription factors, and are able to load and release a molecular cargo (i.e. doxorubicin) in a controlled fashion. In our first model...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452262/ https://www.ncbi.nlm.nih.gov/pubmed/28572901 http://dx.doi.org/10.1039/c6sc03404g |