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Leptin differentially regulates chondrogenesis in mouse vertebral and tibial growth plates

BACKGROUND: Leptin plays an important role in mediating chondrogenesis of limb growth plate. Previous studies suggest that bone structures and development of spine and limb are different. The expression of Ob-Rb, the gene that encodes leptin receptors, is vertebral and appendicular region-specific,...

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Detalles Bibliográficos
Autores principales: Yu, Bo, Jiang, Kaibiao, Chen, Bin, Wang, Hantao, Li, Xinfeng, Liu, Zude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452289/
https://www.ncbi.nlm.nih.gov/pubmed/28569158
http://dx.doi.org/10.1186/s12891-017-1601-6