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Leptin differentially regulates chondrogenesis in mouse vertebral and tibial growth plates
BACKGROUND: Leptin plays an important role in mediating chondrogenesis of limb growth plate. Previous studies suggest that bone structures and development of spine and limb are different. The expression of Ob-Rb, the gene that encodes leptin receptors, is vertebral and appendicular region-specific,...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452289/ https://www.ncbi.nlm.nih.gov/pubmed/28569158 http://dx.doi.org/10.1186/s12891-017-1601-6 |