A knowledge-based framework for the discovery of cancer-predisposing variants using large-scale sequencing breast cancer data

BACKGROUND: The landscape of cancer-predisposing genes has been extensively investigated in the last 30 years with various methodologies ranging from candidate gene to genome-wide association studies. However, sequencing data are still poorly exploited in cancer predisposition studies due to the lac...

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Detalles Bibliográficos
Autores principales: Melloni, Giorgio E. M., Mazzarella, Luca, Bernard, Loris, Bodini, Margherita, Russo, Anna, Luzi, Lucilla, Pelicci, Pier Giuseppe, Riva, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452392/
https://www.ncbi.nlm.nih.gov/pubmed/28569218
http://dx.doi.org/10.1186/s13058-017-0854-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452392/
https://www.ncbi.nlm.nih.gov/pubmed/28569218
http://dx.doi.org/10.1186/s13058-017-0854-1

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