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Defining the ABC of gene essentiality in streptococci

BACKGROUND: Utilising next generation sequencing to interrogate saturated bacterial mutant libraries provides unprecedented information for the assignment of genome-wide gene essentiality. Exposure of saturated mutant libraries to specific conditions and subsequent sequencing can be exploited to unc...

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Detalles Bibliográficos
Autores principales: Charbonneau, Amelia R. L., Forman, Oliver P., Cain, Amy K., Newland, Graham, Robinson, Carl, Boursnell, Mike, Parkhill, Julian, Leigh, James A., Maskell, Duncan J., Waller, Andrew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452409/
https://www.ncbi.nlm.nih.gov/pubmed/28569133
http://dx.doi.org/10.1186/s12864-017-3794-3