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Defining the ABC of gene essentiality in streptococci
BACKGROUND: Utilising next generation sequencing to interrogate saturated bacterial mutant libraries provides unprecedented information for the assignment of genome-wide gene essentiality. Exposure of saturated mutant libraries to specific conditions and subsequent sequencing can be exploited to unc...
Autores principales: | Charbonneau, Amelia R. L., Forman, Oliver P., Cain, Amy K., Newland, Graham, Robinson, Carl, Boursnell, Mike, Parkhill, Julian, Leigh, James A., Maskell, Duncan J., Waller, Andrew S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452409/ https://www.ncbi.nlm.nih.gov/pubmed/28569133 http://dx.doi.org/10.1186/s12864-017-3794-3 |
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