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Potent and reversible lentiviral vector restriction in murine induced pluripotent stem cells
BACKGROUND: Retroviral vectors are derived from wild-type retroviruses, can be used to study retrovirus-host interactions and are effective tools in gene and cell therapy. However, numerous cell types are resistant or less permissive to retrovirus infection due to the presence of active defense mech...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452410/ https://www.ncbi.nlm.nih.gov/pubmed/28569216 http://dx.doi.org/10.1186/s12977-017-0358-1 |