Lymphatic delivery of etanercept via nanotopography improves response to collagen-induced arthritis

BACKGROUND: Evidence suggests lymphatic function mediates local rheumatoid arthritis (RA) flares. Yet biologics that target the immune system are dosed systemically via the subcutaneous (SC) administration route, thereby inefficiently reaching local lymphatic compartments. Nanotopography has previou...

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Detalles Bibliográficos
Autores principales: Aldrich, Melissa B., Velasquez, Fred C., Kwon, Sunkuk, Azhdarinia, Ali, Pinkston, Kenneth, Harvey, Barrett R., Chan, Wenyaw, Rasmussen, John C., Ross, Russell F., Fife, Caroline E., Sevick-Muraca, E. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452411/
https://www.ncbi.nlm.nih.gov/pubmed/28566090
http://dx.doi.org/10.1186/s13075-017-1323-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452411/
https://www.ncbi.nlm.nih.gov/pubmed/28566090
http://dx.doi.org/10.1186/s13075-017-1323-z

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