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Heterologous expression of pikromycin biosynthetic gene cluster using Streptomyces artificial chromosome system
BACKGROUND: Heterologous expression of biosynthetic gene clusters of natural microbial products has become an essential strategy for titer improvement and pathway engineering of various potentially-valuable natural products. A Streptomyces artificial chromosomal conjugation vector, pSBAC, was previo...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452415/ https://www.ncbi.nlm.nih.gov/pubmed/28569150 http://dx.doi.org/10.1186/s12934-017-0708-7 |