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Heterologous expression of pikromycin biosynthetic gene cluster using Streptomyces artificial chromosome system

BACKGROUND: Heterologous expression of biosynthetic gene clusters of natural microbial products has become an essential strategy for titer improvement and pathway engineering of various potentially-valuable natural products. A Streptomyces artificial chromosomal conjugation vector, pSBAC, was previo...

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Detalles Bibliográficos
Autores principales: Pyeon, Hye-rim, Nah, Hee-Ju, Kang, Seung-Hoon, Choi, Si-Sun, Kim, Eung-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452415/
https://www.ncbi.nlm.nih.gov/pubmed/28569150
http://dx.doi.org/10.1186/s12934-017-0708-7