Identification of nuclear genes affecting 2-Deoxyglucose resistance in Schizosaccharomyces pombe

2-Deoxyglucose (2-DG) is a toxic glucose analog. To identify genes involved in 2-DG toxicity in Schizosaccharomyces pombe, we screened a wild-type overexpression library for genes which render cells 2-DG resistant. A gene we termed odr1, encoding an uncharacterized hydrolase, led to strong resistanc...

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Detalles Bibliográficos
Autores principales: Vishwanatha, Akshay, Rallis, Charalampos, Bevkal Subramanyaswamy, Shubha, D'Souza, Cletus Joseph Michael, Bähler, Jürg, Schweingruber, Martin Ernst
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452730/
https://www.ncbi.nlm.nih.gov/pubmed/27481777
http://dx.doi.org/10.1093/femsyr/fow061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452730/
https://www.ncbi.nlm.nih.gov/pubmed/27481777
http://dx.doi.org/10.1093/femsyr/fow061

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