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Clinical significance of the estrogen-modifying enzymes steroid sulfatase and estrogen sulfotransferase in epithelial ovarian cancer

17β-estradiol (E2) can contribute to the progression of epithelial ovarian cancer (EOC). Although the majority of patients with EOC are postmenopausal woman, when de novo estrogen production in the ovary has ceased, ovarian cancer cells remain exposed to estrogens synthesized locally in the cancer c...

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Detalles Bibliográficos
Autores principales: Mungenast, Felicitas, Aust, Stefanie, Vergote, Ignace, Vanderstichele, Adriaan, Sehouli, Jalid, Braicu, Elena, Mahner, Sven, Castillo-Tong, Dan Cacsire, Zeillinger, Robert, Thalhammer, Theresia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452883/
https://www.ncbi.nlm.nih.gov/pubmed/28588698
http://dx.doi.org/10.3892/ol.2017.5969