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Clinical significance of the estrogen-modifying enzymes steroid sulfatase and estrogen sulfotransferase in epithelial ovarian cancer
17β-estradiol (E2) can contribute to the progression of epithelial ovarian cancer (EOC). Although the majority of patients with EOC are postmenopausal woman, when de novo estrogen production in the ovary has ceased, ovarian cancer cells remain exposed to estrogens synthesized locally in the cancer c...
Autores principales: | Mungenast, Felicitas, Aust, Stefanie, Vergote, Ignace, Vanderstichele, Adriaan, Sehouli, Jalid, Braicu, Elena, Mahner, Sven, Castillo-Tong, Dan Cacsire, Zeillinger, Robert, Thalhammer, Theresia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452883/ https://www.ncbi.nlm.nih.gov/pubmed/28588698 http://dx.doi.org/10.3892/ol.2017.5969 |
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