Irradiation of peripheral blood mononuclear cells with 7.5 Gy X-rays prior to donor lymphocyte infusion inhibits proliferation while preserving cytotoxicity, and improves the effectiveness of HSCT in patients with hematological malignancies

The aim of the present study was to explore the effect of different X-ray doses on the proliferation and cytotoxic activity of peripheral blood mononuclear cells (PBMCs), particularly lymphocytes, in order to assess whether this reduces the incidence of graft vs. host disease (GVHD) while preserving...

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Detalles Bibliográficos
Autores principales: Wei, Yong-Qiu, Cen, Xi-Nan, Liu, Hui-Hui, Sun, Yu-Hua, Shi, Yong-Jin, Liu, Wei, Dong, Yu-Jun, Ren, Han-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452913/
https://www.ncbi.nlm.nih.gov/pubmed/28588699
http://dx.doi.org/10.3892/ol.2017.5966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452913/
https://www.ncbi.nlm.nih.gov/pubmed/28588699
http://dx.doi.org/10.3892/ol.2017.5966

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