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Grifolin induces apoptosis and promotes cell cycle arrest in the A2780 human ovarian cancer cell line via inactivation of the ERK1/2 and Akt pathways

Grifolin, a secondary metabolic product isolated from the mushroom Albatrellus confluence, has been demonstrated to possess antitumor activities in a variety of malignant cells. However, the signaling pathways and the molecular mechanisms underlying the anticancer effects of the agent in human ovari...

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Detalles Bibliográficos
Autores principales: Yan, Hong, Che, Xiaoxia, Lv, Qingtao, Zhang, Lili, Dongol, Samina, Wang, Yilin, Sun, Hengzi, Jiang, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452918/
https://www.ncbi.nlm.nih.gov/pubmed/28588729
http://dx.doi.org/10.3892/ol.2017.6092