Cargando…

Grifolin induces apoptosis and promotes cell cycle arrest in the A2780 human ovarian cancer cell line via inactivation of the ERK1/2 and Akt pathways

Grifolin, a secondary metabolic product isolated from the mushroom Albatrellus confluence, has been demonstrated to possess antitumor activities in a variety of malignant cells. However, the signaling pathways and the molecular mechanisms underlying the anticancer effects of the agent in human ovari...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yan, Hong, Che, Xiaoxia, Lv, Qingtao, Zhang, Lili, Dongol, Samina, Wang, Yilin, Sun, Hengzi, Jiang, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452918/ https://www.ncbi.nlm.nih.gov/pubmed/28588729 http://dx.doi.org/10.3892/ol.2017.6092

Ejemplares similares

Grifolin directly targets ERK1/2 to epigenetically suppress cancer cell metastasis
por: Luo, Xiangjian, et al.
Publicado: (2015)

Pharmacological Effects of Grifolin: Focusing on Anticancer Mechanisms
por: Bouyahya, Abdelhakim, et al.
Publicado: (2022)

Grifolin Attenuates White Matter Lesion in Oxygen/Glucose Deprivation
por: Yanqin, Ying, et al.
Publicado: (2017)

Grifolin exhibits anti-cancer activity by inhibiting the development and invasion of gastric tumor cells
por: Wu, Zijian, et al.
Publicado: (2017)

Forkhead transcription factor 1 inhibits endometrial cancer cell proliferation via sterol regulatory element-binding protein 1
por: Zhang, Yifang, et al.
Publicado: (2017)

Curcumin promotes cell cycle arrest and apoptosis of acute myeloid leukemia cells by inactivating AKT
por: Zhou, Hao, et al.
Publicado: (2021)

Theaflavin-3, 3′-digallate induces apoptosis and G2 cell cycle arrest through the Akt/MDM2/p53 pathway in cisplatin-resistant ovarian cancer A2780/CP70 cells
por: TU, YOUYING, et al.
Publicado: (2016)

Identification of upregulated exosomal miRNAs between A2780 and A2780/DDP human ovarian cancer cells by high-throughput sequencing
por: Wang, Huihui, et al.
Publicado: (2023)

Lectin array and glycogene expression analyses of ovarian cancer cell line A2780 and its cisplatin-resistant derivate cell line A2780-cp
por: Zhao, Ran, et al.
Publicado: (2017)

Grifolin, neogrifolin and confluentin from the terricolous polypore Albatrellus flettii suppress KRAS expression in human colon cancer cells
por: Yaqoob, Almas, et al.
Publicado: (2020)

Kaempferol Induces G2/M Cell Cycle Arrest via Checkpoint Kinase 2 and Promotes Apoptosis via Death Receptors in Human Ovarian Carcinoma A2780/CP70 Cells
por: Gao, Ying, et al.
Publicado: (2018)

Design and synthesis of water-soluble grifolin prodrugs for DNA methyltransferase 1 (DNMT1) down-regulation
por: Wang, Liguo, et al.
Publicado: (2021)

Redox proteome analysis of auranofin exposed ovarian cancer cells (A2780)
por: Chiappetta, Giovanni, et al.
Publicado: (2022)

Nitric oxide affects cisplatin cytotoxicity oppositely in A2780 and A2780‐CDDP cells via the connexin32/gap junction
por: Fan, Lixia, et al.
Publicado: (2020)

5-Demethylnobiletin mediates cell cycle arrest and apoptosis via the ERK1/2/AKT/STAT3 signaling pathways in glioblastoma cells
por: Zhang, Xuehua, et al.
Publicado: (2023)

Functional and transcriptomic characterization of carboplatin-resistant A2780 ovarian cancer cell line
por: Viscarra, Tamara, et al.
Publicado: (2019)

Effect of the HDAC Inhibitor on Histone Acetylation and Methyltransferases in A2780 Ovarian Cancer Cells
por: Natarajan, Umamaheswari, et al.
Publicado: (2021)

Investigation of Anticancer Properties of Monoterpene-Aminopyrimidine Hybrids on A2780 Ovarian Cancer Cells
por: Nagy, Viktória, et al.
Publicado: (2023)

Pleuromutilin Inhibits Proliferation and Migration of A2780 and Caov-3 Ovarian Carcinoma Cells and Growth of Mouse A2780 Tumor Xenografts by Down-Regulation of pFAK2
por: Zhang, Bo, et al.
Publicado: (2020)

Inactivation/deficiency of DHODH induces cell cycle arrest and programed cell death in melanoma
por: Liu, Lichao, et al.
Publicado: (2017)

Discovering simple phenylboronic acid and benzoxaborole derivatives for experimental oncology – phase cycle-specific inducers of apoptosis in A2780 ovarian cancer cells
por: Psurski, Mateusz, et al.
Publicado: (2018)

Retracted: Pleuromutilin Inhibits Proliferation and Migration of A2780 and Caov-3 Ovarian Carcinoma Cells and Growth of Mouse A2780 Tumor Xenografts by Down-Regulation of pFAK2
por: Zhang, Bo, et al.
Publicado: (2021)

A biscarbene gold(I)-NHC-complex overcomes cisplatin-resistance in A2780 and W1 ovarian cancer cells highlighting pERK as regulator of apoptosis
por: König, Philipp, et al.
Publicado: (2023)

Effects Of Adenosine On Apoptosis Of Ovarian Cancer A2780 Cells Via ROS And Caspase Pathways
por: Xia, Bing, et al.
Publicado: (2019)

Cajanol Sensitizes A2780/Taxol Cells to Paclitaxel by Inhibiting the PI3K/Akt/NF-κB Signaling Pathway
por: Sui, Ming, et al.
Publicado: (2021)

Inactivation of nucleolin leads to nucleolar disruption, cell cycle arrest and defects in centrosome duplication
por: Ugrinova, Iva, et al.
Publicado: (2007)

Conditional inactivation of PDCD2 induces p53 activation and cell cycle arrest
por: Granier, Celine J., et al.
Publicado: (2014)

A2780 human ovarian cancer cells with acquired paclitaxel resistance display cancer stem cell properties
por: HAN, XIAOFENG, et al.
Publicado: (2013)

A2780 human ovarian cancer cells with acquired paclitaxel resistance display cancer stem cell properties
por: Han, Xiaofeng, et al.
Publicado: (2022)

Chemotherapeutic potential of Cayratia trifolia L nhexane extract on A2780 cells
por: Palanisamy, Chella Perumal, et al.
Publicado: (2021)

Extracellular Matrix Proteins Expression Profiling in Chemoresistant Variants of the A2780 Ovarian Cancer Cell Line
por: Januchowski, Radosław, et al.
Publicado: (2014)

Cytotoxic Effects of Strawberry, Korean Raspberry, and Mulberry Extracts on Human Ovarian Cancer A2780 Cells
por: Lee, Dahae, et al.
Publicado: (2016)

Heparin antagonizes cisplatin resistance of A2780 ovarian cancer cells by affecting the Wnt signaling pathway
por: Pfankuchen, Daniel Bastian, et al.
Publicado: (2017)

Effects of Adenosine on Apoptosis of Ovarian Cancer A2780 Cells via ROS and Caspase Pathways [Corrigendum]
Publicado: (2020)

Apoptosis Induction with Combined Use of Cisplatin and Fisetin in Cisplatin-Resistant Ovarian Cancer Cells (A2780)
por: Jafarzadeh, Samira, et al.
Publicado: (2021)

Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer
por: Roy, Sanjit K, et al.
Publicado: (2010)

β-Thujaplicin induces autophagic cell death, apoptosis, and cell cycle arrest through ROS-mediated Akt and p38/ERK MAPK signaling in human hepatocellular carcinoma
por: Zhang, Guangya, et al.
Publicado: (2019)

Anticancer Activity of Mukonal Against Human Laryngeal Cancer Cells Involves Apoptosis, Cell Cycle Arrest, and Inhibition of PI3K/AKT and MEK/ERK Signalling Pathways
por: Li, Liu, et al.
Publicado: (2018)

Houttuynia cordata Thunb. Hexane fraction induces MDA-MB-231 cell apoptosis via caspases, ER stress, cell cycle arrest and attenuated Akt/ERK signaling
por: Inthi, Pitsinee, et al.
Publicado: (2023)

Pterostilbene Induces Cell Apoptosis and Cell Cycle Arrest in T-Cell Leukemia/Lymphoma by Suppressing the ERK1/2 Pathway
por: Chang, Gaomei, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_lp9d8n7mf7b190at0fv4ricti0