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Reduction of miR-21 induces SK-N-SH cell apoptosis and inhibits proliferation via PTEN/PDCD4

MicroRNA (miR/miRNA)-21 is a well-known oncogenic miRNA that is overexpressed in various types of tumors. The tumor-suppressor genes programmed cell death 4 (PDCD4) and phosphatase tensin homologue (PTEN), are targets of miR-21, and are underexpressed in several types of cancer. However, the express...

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Detalles Bibliográficos
Autores principales: Wang, Zuopeng, Yao, Wei, Li, Kai, Zheng, Na, Zheng, Chao, Zhao, Xiaolong, Zheng, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452970/
https://www.ncbi.nlm.nih.gov/pubmed/28599474
http://dx.doi.org/10.3892/ol.2017.6052