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Periostin suppresses in vivo invasiveness via PDK1/Akt/mTOR signaling pathway in a mouse orthotopic model of bladder cancer

Periostin is an extracellular matrix protein involved in the regulation of intercellular adhesion. The present study investigated the in vivo tumor suppressor function of periostin in a mouse orthotopic model of bladder cancer. Retroviral vectors were used to transfect human bladder cancer UMUC-3 ce...

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Detalles Bibliográficos
Autores principales: Kim, Chul Jang, Tambe, Yukihiro, Mukaisho, Ken-Ichi, Sugihara, Hiroyuki, Kageyama, Susumu, Kawauchi, Akihiro, Inoue, Hirokazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452989/
https://www.ncbi.nlm.nih.gov/pubmed/28599427
http://dx.doi.org/10.3892/ol.2017.6004