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Periostin suppresses in vivo invasiveness via PDK1/Akt/mTOR signaling pathway in a mouse orthotopic model of bladder cancer
Periostin is an extracellular matrix protein involved in the regulation of intercellular adhesion. The present study investigated the in vivo tumor suppressor function of periostin in a mouse orthotopic model of bladder cancer. Retroviral vectors were used to transfect human bladder cancer UMUC-3 ce...
Autores principales: | Kim, Chul Jang, Tambe, Yukihiro, Mukaisho, Ken-Ichi, Sugihara, Hiroyuki, Kageyama, Susumu, Kawauchi, Akihiro, Inoue, Hirokazu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452989/ https://www.ncbi.nlm.nih.gov/pubmed/28599427 http://dx.doi.org/10.3892/ol.2017.6004 |
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