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A conditionally replicating adenovirus expressing IL-24 acts synergistically with temozolomide to enhance apoptosis in melanoma cells in vitro

Malignant melanoma is characterized by suppressed apoptosis in tumor cells and high levels of invasion. Temozolomide (TMZ) is one of the most effective single chemotherapeutic agents for patients with malignant melanoma, but resistance develops quickly and frequently. Therapeutic cytokines such as i...

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Detalles Bibliográficos
Autores principales: Liang, Zhen, Yang, Chun-Sheng, Gu, Feng, Zhang, Lan-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453041/
https://www.ncbi.nlm.nih.gov/pubmed/28599419
http://dx.doi.org/10.3892/ol.2017.6007